The former Everton junior netted his 176th goal for the Red Devils against Liverpool, as United beat their rivals 1-0 in a tight contest.
The England captain reached the landmark after 358 games, which is 100 more than it took Henry to rack up his tally of 175 goals.
The Frenchman averaged 0.68 goals per game during his career at the Gunners, while Rooney has been scoring at a rate of 0.46 goals per game.
Between the two, Rooney has had greater team success, as he has won five Premier League titles during his 12 seasons with the Old Trafford outfit.
Henry won just two league crowns with the Gunners between 1999 and 2007 before a brief return on loan at the Emirates Stadium in the 2011-12 campaign.
Rooney has been under intense scrutiny following United's poor start to the season and a poor goal return which saw the forward net just twice for his club between August and December.
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2016, however, has been a fresh start for the experienced forward, scoring five times in United's four January fixtures and adding to his career total of 242 goals for the Manchester club.
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