UEFA Champions League holders Chelsea moved to the top of Group H after thrashing Juventus 4-0 at Stamford Bridge.
Trevor Chalobah, Reece James, Callum Hudson-Odoi and Timo Werner got on the scoresheet for the Blues.
Chelsea leapfrogged the Bianconeri to top spot on goal difference with the drubbing and with both sides already qualified for the next round, the group winner will be decided on matchday six.
Malmo and Zenit St Petersburg settled for a share of the spoils after playing to a 1-1 draw in Group H.
Soren Rieks gave Malmo the lead in the 28th minute. Zenit had Dimtiri Chistyakov sent off in the 86th minute but still managed to claim a point through Yaroslav Rakitskiy in the second minute of stoppage time.
Zenit remain three points ahead of Malmo, who have one point and sit bottom.
Lille claimed a narrow 1-0 win over RB Salzburg in a hard-fought encounter in Group G.
Jonathan David scored the only goal of the game on the half-hour mark.
Lille moved above Salzburg to the top of the group, leading the Austrians by one point.
LaLiga Sevilla kept their round of 16 hopes alive with a 2-0 victory over Wolfsburg at Estadio Ramón Sánchez Pizjuan.
Joan Jordan gave the Seville outfit an early lead with 12 minutes gone and Rafa Mir wrapped it up in the fifth minute of stoppage time.
Sevilla leapfrogged Wolfsburg into third, with the group still wide open going into the final matchday.
Lille have eight points, Salzburg have seven points, Sevilla have six points and Wolfsburg have five points in the tightest of the groups.
FC Barcelona were held to a 0-0 draw by Benfica at home in Group E.
Despite Barca enjoying 66 percent of the possession and having 14 shots in the encounter, they failed to break down a stubborn Benfica outfit.
Barca failed to secure their qualification as they are only two points above Sevilla, who are in third place and can still qualify.
Young Boys and Atalanta played to a thrilling 3-3 draw at Stadion Wankdorf on Tuesday night.
Theoson Siebatchu, Vincent Sierro and Silvan Hefti netted for the Swiss, while Duvan Zapata, Jose Luis Palomino and Luis Muriel found the back of the net for the Bergamo outfit.
Atalanta are still in contention for the knockout stages as they are just one point behind second-placed Villareal, while Young Boys won't make the last 16.
