England relinquished top spot in Group 2 of League A following a 1-0 loss to Denmark at Wembley Stadium.
The Three Lions were reduced to 10 men on 31 minutes when defender Harry Maguire picked up his second yellow card of the game.
The visitors took the lead four minutes later when former Tottenham Hotspur star Christian Eriksen converted from the penalty spot.
Fortunately for Danes, Eriksen's first-half spot-kick was enough to do the damage which sees Gareth Southgate's side slip to third while Denmark move up to second spot.
Belgium moved top of Group 2 after defeating Iceland 2-1 on Wednesday night.
The Red Devils raced into a ninth-minute lead through Romelu Lukaku, before Birkir Már Sævarsson restored parity for the visitors on 17 minutes.
Lukaku put the Belgians ahead before the break with his second goal on the night from the penalty spot in the 36th minute.
Italy were denied the chance to move top of Group 1 after playing to a 1-1 draw with the Netherlands.
After drawing a blank against Poland over the weekend, Lorenzo Pellegrini opened the scoring for the Azzurri in the 16th minute.
The Dutch were back on level terms just over 10 minutes later thanks to Manchester United midfielder Donny van de Beek.
Neither side were able to find a winning goal, as the Italians sit in second spot while the Dutch find themselves in third spot.
