Nigeria 1-1 Ghana (1-1 on agg.)
Ghana have qualified for the 2022 FIFA World Cup after securing a 1-1 draw in the second leg on Tuesday night.
Scroll through the gallery above to see the five African nations to have qualified for the World Cup.
The Black Stars were unchanged from the goalless first leg on Friday, while the Super Eagles recalled Bassey and Emmanuel Dennis while Ademola Lookman was given his debut.
The visitors got off to the perfect start when Thomas Partey opened the scoring on 10 minutes with a strike from distance.
Nigeria weren't behind for too long when Lookman won a penalty, which was tucked away by William Troost Ekong in the 22nd minute.
Victor Osimhen had the ball in the back of the net 10 minutes before the halftime break, but the goal was ruled out by VAR for offside.
The Super Eagles were unable to find another way past the Ghanaians, who managed to secure their ticket to Qatar on the away goals rule.
Algeria 1-2 Cameroon (2-2 agg.)
Cameroon sealed passage to the World Cup with a 2-1 extra-time win over Algeria.
The Algerians came into the second leg with a 1-0 lead from the first leg on Friday.
However, the Indomitable Lions got an away goal of their own thanks to Eric Maxim Choupo-Moting's 22nd minute strike.
With the tie evenly poised at 1-1, the clash went on to extra-time where Algeria thought they had clinched it through Ahmed Touba's 117th minute strike.
However, Karl Toko Ekambi got the winner for Cameroon in the dying seconds to send his side to the World Cup on the away goals rule.
Morocco 4-1 Congo DR (5-2 on agg.)
Morocco will once again be competing at the World Cup after thrashing the Democratic Republic of Congo 4-0 on Tuesday night.
Congo had the slight advantage coming into the tie after a 1-1 draw in the first leg.
However, the Moroccans showed no mercy in the second leg as Azzedine Ounahi bagged a brace while Achraf Hakimi and Tarik Tissoudali also got on the scoresheet.
Ben Malango did pull a goal back for the visitors on 77 minutes, but it proved to be nothing more than a consolation.
Tunisia 0-0 Mali (1-0 agg.)
Tunisia will be be heading back to the World Cup finals after a goalless draw against Mali in the second leg of their play-off.
Mali were unable to overturn a first-leg 1-0 loss, as their wait for a first World Cup appearance continues.
Senegal 1-0 Egypt (1-1 on agg.)
Senegal secured their ticket to the World Cup in Qatar after defeating Egypt on penalties.
The Pharaohs came into the encounter with the advantage after securing a 1-0 in the first leg a few days ago in Cairo.
However, the African champions levelled matters in the tie after just four minutes when Hamdi Fathi deflected the ball into his own net.
Egypt were also forced to make two changes in the first half as Rami Rabiaa and Omar Gaber picked up injuries and were replaced by Emam Ashour and Ayman Ashraf.
Neither were able to find another goal for the remainder of the 90 minutes, which forced the encounter into extra-time.
However, just as it was in the Africa Cup of Nations this year, the outcome was decided by a penalty shoot-out as Senegal triumphed 3-1 on penalties to book their spot at the World Cup.
Who are the 10 highest-ranked African nations in FIFA's rankings? Take a look below:
