Banyana Banyana will face Botswana in an international friendly on Sunday before jetting off to the FIFA Women's World Cup.
Desiree Ellis revealed her final 23-player squad for the tournament last week, but they will play one last friendly on home soil before leaving.
SAFA have confirmed the match will be used a sand-off for the national, with the clash taking place at the Tsakane Stadium this Sunday.
Read: Banyana Confirm Final Squad For Women's World Cup
Ellis has urged the supporters come out in their numbers for the final home game before flying off to Australia.
"We just want to thank the Football Association getting us a send-off match. We know it has been a difficult task, we are really grateful and we ask the fans to come out in their numbers to support this team and to give us a fantastic send-off," Ellis told safa.net.
"We look forward to playing the match and we thank Botswana as well for coming forward to play this send-off match.
"It's a huge match for us, the last match before we leave the shores of South Africa. We really want to put up a good performance and again we urge the fans to come out and really give us a fantastic send-off."
South Africa will also take on South American side Costa Rica in their final friendly next month.
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