Tottenham Hotspur and Fiorentina will have it all to play for in the second leg, after playing out to a 1-1 draw at White Hart Lane on Thursday night.
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Spurs went ahead through fine volley from Roberto Soldado as early as the sixth minute, however the Italian outfit grabbed an important away goal in the 36th minute, as Jose Basanta tapped home from close range after Hugo Lloris failed to deal with a cross.
A brace from Rodrigo Palacios and a solitary strike from Xherdan Shaqiri helped Inter Milan secure a 3-3 with Glasgow Celtic at Celtic Park on Thursday evening.
Napoli have one foot in the Last 16, after they thumped Trabzonzspor 4-0 at the Huseyin Avni Aker Stadium in their first leg tie.
Goals from Henrique, Gonzalo Higuain, Manolo Gabbiadini and Duvan Zapata secured the win for Rafael Benitez's side.
A brace from Bas Dost handed Wolfsburg a 2-0 win over Sporting Lisbon in their first leg clash at the Volkswagen Arena.
Colin Kazim-Richards cancelled Gervinho's first half strike, as Feyenoord and AS Roma played out to a 1-1 draw at the Stadio Olimpico on Thursday night.
Vicente Iborra scored the only goal of the game to help defending Europa League champions, Sevilla, claim a 1-0 win over Borussia Monchengladbach.
Goals from Ikechukwu Uche and Denis Cheryshev earned Villarreal a 2-1 win over Red Bull Salzburg in their first leg encounter at Estadio El Madrigal.
The rest of Thursday night's results:
Torino 2-2 Athletic Bilbao
AaB 1-3 Club Brugge
Dnipro Dnipropetrovsk 2-0 Olympiacos
PSV Eindhoven 0-1 Zenit St. Petersburg
Ajax Amsterdam 1-0 Legia Warsaw
Guingamp 2-1 Dynamo Kiev
Anderlecht 0-0 Dynamo Moscow
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