Southampton 0-0 Manchester City
Manchester City endured a frustrating afternoon after being held to a goalless draw by relegated Southampton at St Mary's Stadium.
As a result, City missed the chance to move level on points with second-place Arsenal, who face Liverpool at Anfield on Sunday.
Pep Guardiola's charges will now switch focus to next week's FA Cup final against Crystal Palace.
Bournemouth 0-1 Aston Villa
Aston Villa kept their UEFA Champions League hopes alive after defeating AFC Bournemouth 1-0 at the City Ground on Saturday evening.
Ollie Watkins got the game's only goal after being set up by Morgan Rodgers on the stroke of halftime.
Villa, however, did finish the game with ten men after Jacob Ramsey was given his marching orders after picking up his second yellow card on 80 minutes.
The win moves Villa into sixth spot, level on points with Chelsea who face Newcastle United on Sunday.
Fulham 1-3 Everton
Everton rallied from behind to secure a 3-1 victory away to Everton on Saturday afternoon.
The hosts took the lead through Raul Jimenez's effort in the 17th minute before Vitalii Mykolenko restored parity for the visitors on the stroke of halftime.
The Toffees completed the turnaround in the second half, with Michael Keane and Beto getting the goals.
Wolverhampton Wanderers 0-2 Brighton and Hove Albion
Brighton and Hove Albion got back to winning ways in the Premier League after defeating Wolverhampton Wanderers 2-0 on Saturday.
Goals from Danny Welbeck and Brajan Gruda guided the Seagulls to maximum points at Molinuex Stadium.
Ipswich Town 0-1 Brentford
Brentford made it four successive wins in the league after defeating relegated Brentford 1-0 on Saturday afternoon.
Kevin Schade got the game's only goal after turning home a cross from Bryan Mbuemo.