Banyana Banyana's trip to the Netherlands has been called off five squad members tested positive for Covid-19.
The national side were scheduled to leave for the Netherlands on Monday as part of their CAF Africa Women's Cup of Nations qualifiers.
However, SAFA confirmed that five players had contracted the coronavirus, forcing the entire travelling delegation to isolate.
"This is a difficult time where we are in the middle of the third wave in our country, and unfortunately Banyana Banyana has not been spared from this pandemic," Head coach Desiree Ellis told SAFA.net.
"Due to positive cases in our camp, the full delegation has been put into isolation, and we will therefore not be able to honour the friendly fixture against the Netherlands.
"At this moment, of utmost importance is the health of everyone – both us and our opponents – and football takes second place.'
"Let me take this opportunity to thank Netherlands for the invite and also wish them all the best at the upcoming Tokyo Olympic Games.
"To my fellow South Africans, please take extra care and caution out there – Covid-19 is real, let's protect each other by wearing masks in public, keeping a safe distance and sanitizing all the time.''