RB Leipzig reclaimed their fourth spot on the Bundesliga table after thumping Hoffenheim 3-0 at Red Bull Arena.
Christopher Nkunku, Marcel Halstenberg and Dominik Szoboszlai all scored in the first stanza for rampant Leipzig.
Leipzig moved to within one point of third-placed Bayer Leverkusen while Hoffenheim remained in sixth place on the table.
The Red Bulls will turn their focus to the UEFA Europa League when they travel to Atalanta in the quarter-final second-leg on Thursday evening while Hoffenheim will resume their league schedule at home against Greuther Furth on Sunday evening.
Freiburg boosted their chances of qualifying for the UEFA Champions League after beating Eintracht Frankfurt 2-1 at Deutsche Bank Park.
Vincenzo Grifo broke the deadlock for Freiburg just before the half-hour mark but Filip Kostic levelled matters for Eintracht early in the second stanza.
Nils Petersen restored the lead for the visitors 21 minutes before time and Eintracht were unfortunate not to salvage a point in the last four minutes after Kristijan Jakic's goal was disallowed by the Video Assistant Referee (VAR) for offside.
Freiburg remained in fifth place on the log, three points behind fourth-placed RB Leipzig while Eintracht remained in ninth place, five points off the European qualification places.
Frankfurt will switch their focus to the UEFA Europa League when host Barcelona in the quarter-final second-leg on Thursday night while Freiburg will resume their league schedule at home against Bochum next Saturday.
Bayer Leverkusen missed the chance to solidify their third spot on the log after they were held to a goalless stalemate by Bochum at Vonovia Ruhrstadion.
Danilo Soares came close to breaking the deadlock for Bochum just before the half-time break with a strike from range that rattled the crossbar.
However, Moussa Diaby had the biggest chance for Bayer in the 65th minute from the penalty spot but missed the target.
Leverkusen held on to third spot by a point above fourth-placed RB Leipzig while Bochum dropped down to 12th on the table.
Bochum will be back in action next Saturday when they host Freiburg while Leverkusen will be at home against RB Leipzig a day later.