The Telkom Knockout quarter-final draw took place on Tuesday evening, and the Soweto derby will headline the next round - Check out the full draw.
Click through the gallery to see the eight sides left in the tournament.
There will be a different name on the trophy this season after Baroka FC were eliminated at the hands of SuperSport on penalties.
For the second round in a row, the draw was seeded although Mamelodi Sundowns, Orlando Pirates, SuperSport United and Highlands Park were the only seeded teams in the round of 16.
The biggest tie of the round will see Soweto giants Kaizer Chiefs host cross-town rivals Orlando Pirates for a spot in the semi-finals.
Mamelodi Sundowns were the biggest winners in the last round with a 5-0 triumph over AmaZulu, and they have now been awarded with a trip to Chippa United.
The Premier Soccer League will announce the dates and venues for the fixtures in due course.
Kaizer Chiefs v Orlando Pirates
SuperSport United v Golden Arrows
Chippa United v Mamelodi Sundowns
Maritzburg United v Highlands Park