Happy Wanderers 0-1 Royal Eagles
National First Division side Royal Eagles advanced to the next round after defeating Wanderers 1-0 on Sunday afternoon.
Former Mamelodi Sundowns striker Mame Niang scored the game's only goal in the 17th minute.
Mariveni United 1-3 EC Bees
EC Bees ensured their Nedbank Cup journey continued after they defeated Mariveni United 3-1 on Sunday afternoon.
Bees were dumped out by Orlando Pirates in the last 32 in the previous campaign.
Steenberg United 3-1 Orbit College
Steenberg United secured their ticket in the next round of the competition after defeating Orbit College 3-1.
Mika-iel Hendricks bagged a brace, while Waseen George also netted for the home side.
Katlego Motsoikha bagged a consolation for Orbit College.