Arsenal 3-0 Rennes (4-3 on agg.)
Arsenal advanced to the quarter-finals of the with a 3-0 second-leg win at the Emirates
After losing the first leg 3-1, the Gunners raced in front after just five minutes when Pierre-Emerick Aubameyamg slotted home Aaron Ramsey's cross.
The lead was doubled 10 minutes later when Aubameyang turned provider to pick out Ainsley Maitland-Niles, who nodded home to make it 3-3 on aggregate.
The last eight spot was sealed in the 72nd minute as Aubameyang completed his brace with a close range finish.
Villarreal 2-1 Zenit (5-2 on agg.)
The Yellow Submarine already had one foot in the next round after winning 3-1 in the first leg, but the tie was sealed as Gerard Moreno and Carlos Bacca secured a 2-0 win in the second leg.
Former Chelsea star Branislav Ivanovic bagged a consolation for Zenit in second-half stoppage time.
Slavia Praha 4-3 Sevilla (6-5 on agg/)
Sevilla's Europa League journey came to an end after losing 4-3 to Slavia Praha in extra-time for 6-5 aggregate win.
Praha gave themselves some hope heading into the clash after the two sides drew 2-2 in Spain last week.
Michael Ngadeu-Ngadjui, Tomáš Souček, Mick van Buren and Ibrahim Traore were on target for the hosts to cancel out strikes from Wissam Ben Yedder, Munir and Franco Vazquez.
Inter Milan 0-1 Eintracht Frankfurt (0-1 on agg.)
Inter Milan were dumped out of the tournament after losing 1-0 to Eintracht Frankfurt at San Siro.
The tie was evenly poised after the first leg ended goalless, but Frankfurt got the all important winning goal thanks to Luka Jovic in the fifth minute.
Benfica 3-0 Dinamo Zagreb (3-1 on agg.)
Benfica needed extra-time to secure a spot in the last eight after defeating Dinamo Zagreb 3-0 on Thursday night.
The Portuguese outfit suffered a 1-0 defeat in the first leg, but they were back on the level terms in the 71st minute in the second leg through Jonas' strike.
The clash sent the game into extra-time, where Francisco Ferreira secured the second goal before Alex Grimaldo sealed the win in the 105th minute.