Atletico Madrid 2-0 Sporting Lisbon
Atletico Madrid will take a healthy two-goal lead into the second leg after defeating Sporting Lisbon 2-0 at the Wanda Metropolitano.
Koke opened the scoring for Atletico after just one minute, while Antoine Griezmann doubled the lead five minutes before the break.
Lazio 4-2 Red Bull Salzburg
Lazio and RB Salzburg played out a six-goal spectacle, with the former claiming a 4-2 win at the Stadio Olimpico.
Senad Lulic, Marco Parolo, Felipe Anderson and Ciro Immobile were on target for the Serie A outfit.
The Austrian outfit did manage to secure two valuable away goals thanks to strikes from Valon Berisha and Takumi Minamino.
RB Leipzig 1-0 Marseille
Timo Werner's first-half strike was enough to hand RB Leipzig a 1-0 win over Olympique Marseille at the Red Bull Arena.