With just Olivier Giroud and Nicklas Bendtner to rely on in attack in recent times, their squad has had a thin veneer.
But Saints old boy Theo Walcott is back in action after his lengthy spell in the treatment room, and he is available to give Arsenal a pacey option upfront.
"Strikers who get behind the defenders have a very important quality and Theo has that quality," Gunners boss Arsene Wenger told the club’s official website on Thursday.
"Of course you miss a player like Theo Walcott. Theo had a good start to the season, he scored goals, he provided chances and had assists. He can always give you a different option in the game and that is of course vital.
"He has not played for a long time, of course, he has not played even a reserve team game, but I will put him in the squad on Saturday.
"If you look at our [recent] results our balance was not too bad. But Theo has different qualities to other players and I am very pleased that he's back.”
Also encouraging for the silverware starved Emirates outfit is Wenger’s prognosis for German forward Lukas Podolski.
Podolksi has been another long-term absentee from the Gunners first-team squad, but his return from injury now appears to be less than a month away.
"Podolski is not too far away, I would say three weeks. He is doing fitness training on the pitch. He starts to do some ball work too, he still needs two or three weeks before we see him on the pitch for Arsenal," Wenger said.
If Arsenal can maintain their current form when their full quota of players is available, and if they purchase wisely in January, it will be very difficult for any team to dislodge them from the upper reaches of the Premier League this season.