Manchester United’s young utility defender, Phil Jones, has been diagnosed with shingles, and could miss up to one month of football.
Shingles is a viral disease characterised by a painful rash or blisters.
England Under 21 coach Stuart Pearce confirmed Jones’ diagnosis on Monday evening, ruling him out of contention for the young Three Lions’ match against Sweden on Tuesday night.
Jones had earlier been omitted from Manchester United’s squad which saw off Fulham 1-0 at the weekend.
He is also likely to miss United’s Champions League trip to Real Madrid next week.
"It's a shame. You want your good players to be here," Pearce said.
"But Phil has picked up shingles and there's not a lot we can do about it. But it means someone else gets a chance."
With players like Jordan Henderson, Jonjo Shelvey and Raheem Sterling, who have all won senior England caps in the past 12 months, things are looking up for Pearce and the Under 21s, who have their sights set on glory at the European Championships later this year.