Real Betis 3-1 Valencia: Betis got off to a perfect start as they went 3-0 ahead within 34 minutes. Jorge Molina fired in the opener in the ninth minute before Salvador Sevilla struck twice. Valencia put on a much improved performance after the interval but could only pull a goal back through Ricardo Costa as Betis claimed the spoils.
Malaga 5-0 Rayo Vallecano: Mounir El Hamdaoui starred as his struck a hat-trick to inspire Malaga to a comfortable win over Rayo Vallecano. Francisco Portillo and Eliseu completed the rout as Vallecano failed to find a response.
Granada 1-0 Espanyol: Manu Lanzarote put the visitors ahead in the 76th minute and Granada's hopes of a late comeback were dashed when Odion Ighalo was sent off six minutes later.
Getafe 2-1 Osasuna: Roberto Torres put Osasuna in the lead in the 11th minute but Miku scored on either side of the break to turn the result around.
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