Arsenal may be top of the table now, but they had to overcome a rickety start to get there.
Both Manchester clubs have also tasted defeat already this season, and their starts to the campaign under new managers have hardly been smooth sailing.
The same can be said for Chelsea, who have dropped five points under The Special One,
Liverpool meanwhile, were top of the table for a few weeks, but are hardly likely to be title challengers when push comes to shove.
Of the big teams, only Tottenham Hotspur have so far avoided talk of a mini crisis at this early juncture of the season.
Tied with their North London rivals at the top of the table, against whom they have suffered their only defeat, they have been a model of positive consistency.
With so many new players arriving to replace the departed Gareth Bale, it is intriguing to see how quickly manager Andre Villas-Boas can get his new charges to click.
He has brought some eye-catching signings to White Hart Lane, and Spurs have the potential to do better this season than ever before in the Premier League.
They welcome Chelsea to the Lane at the weekend, and will do so with great confidence after thrashing Aston Villa in the Capital One Cup.
Spurs are certainly on a high, and their German midfielder, Lewis Holtby, believes that their strong squad and good form means that they are genuine trophy contenders this season.
Whether it comes in the League Cup, Europa League or Premier League, Holtby says silverware is within Spurs’ grasp.
"Silverware is silverware. There's four cups to play for and you want to win all of them," Holtby said.
"If you want to go to the top as a professional footballer you try to win every game and you try to win every trophy.
“That's what we are trying to do and we just have to work like we have as a team the last couple of weeks. We have a big chance of winning something but it is a very long season."
Meanwhile, having tasted derby defeat against the Gunners, Holtby says Spurs are determined to set things right this weekend, when Chelsea make the short trip across London for a 90 minute spat over local bragging rights.
"Unfortunately we lost the derby [against Arsenal] but we did the job in winning against the teams beneath us,” he said.
“We have to keep that up. Especially against Chelsea in the London derby, it is very important to win a big game like that to stay up top and give us the confidence we need."