The Indomitable Lions qualified for the World Cup Finals in Brazil after beating Tunisia 4-1 at the Stade Omnisport Ahmadou Ahidjo in Yaounde, Cameroon.
Jean Makoun got a brace in the second-half, after first-half strikes from Pierre Achille Webo and Benjamin Moukandjo. Ahmed Akaichi scored for Tunisia.
The first-leg of this World Cup qualifying play-off tie, played a month ago in Rades, ended in a goalless draw.
Cameroon got off to the perfect when Pierre Achille Webo opened the scoring for the hosts in the fifth minute. The 31 year old making no mistake from the left of goal as he placed the ball from a tight angle into the opposite corner of the goal, past a diving Moez Ben Cherifia.
In the 16th minute Benout Assou-Ekotto tried a long range effort, and the ball bounced awkwardly in front of Ben Cherifia, but the goalkeeper was able to parry it away from goal.
In the 23rd minute Cameroon thought they had a penalty as the ball seemed to strike Syam Ben Youssef's arm, but the referee waved play on.
Cameroon doubled their lead on the half hour mark through a great piece of individual skill by Benjamin Moukandjo.
He dribbled through three defenders and their challenges before striking the ball from the edge of the area into the bottom left corner to make it 2-0.
In the 38th minute Samuel Eto'o had a chance but his shot from the right of goal went over the bar.
A minute later Syam Ben Youssef had an opportunity for Tunisia, but his header from a Wissem Ben Yahia set piece never threatened Charles Itandje's goal.
The second half started with the perfect response by Tunisia, when in the 52nd minute half-time substitute Ahmed Akaichi ran onto a good through ball and blasted a great shot home to make it 2-1.
For a while it looked like Tunisia would get back into this tie, but it wasn't long before Cameroon regained control of the game.
Stephane Mbia had a chance from a corner in the 63rd minute, but his header took a deflection and just bounced over the goal.
Cameroon made it 3-1 when an unmarked Jean Makoun headed in from Assou-Ekotto's corner in the 66th minute.
In the 69th minute Fakhereedine Ben Youssef tried a shot from right of the goal for Tunisia but it flew over the bar.
Moukandjo should have had another in the 71st minute but after Ben Cherifia saved his first attempt, he shot over from in front of goal.
In the 77th minute Eric Maxim Choupo-Moting did well to turn and shoot from just inside the box, but Ben Cherifia got down to make the save.
Makoun beat the offside-trap in the 84th minute but instead of going for his brace, he chose to cross, and Tunisia were able to clear the ball.
Makoun did get his second a minute later, and wrapped up the tie, when he pounced on the ball after it struck the upright from Choupo-Moting's shot, and calmly finished to make it 4-1.