The draw for the quarterfinal stage of the Capital One Cup was made on Wednesday evening.
Manchester City, who thrashed Crystal Palace 5-1, will host Championship outfit Hull City, who eliminated Leicester City via a penalty shoot-out.
Jurgen Klopp secured his first win as Liverpool manager and their reward is trip to St. Mary's to face Southampton.
Giants killers, Middlesbrough, will play host to Everton, another Championship outfit, Sheffield Wednesday, travel to Stoke City.
The ties will be played during the week of 30 November.