Ethiopia 2-0 Egypt
Egypt, who were without Mohamed Salah, suffered a surprise 2-0 loss to Ethiopia in their second Group D clash on Thursday evening at Bingu National Stadium in Malawi.
Dawa Hotessa broke the deadlock for the Walia Ibex on 21 minutes and Shimelis Bekele doubled their lead six minutes before halftime.
Ethiopia, who got their campaign off the mark, beat Egypt for the first time in 33 years.
Nigeria 2-1 Sierra Leone
Nigeria enjoyed a winning start in Group A after a come-from-behind 2-1 win over Sierra Leone on Thursday evening at Abuja National Stadium.
Jonathan Morsay opened the scoring for the Leone Stars 11 minutes into the encounter but Alexander Iwobi levelled matters for the Super Eagles five minutes later.
Victor Osimhen scored what proved to be the winner for Jose Peseiro's charges just before the half-time break.
Burundi 0-1 Cameroon
Cameroon got their Group C campaign off to a winning start after edging Burundi 1-0 on Thursday afternoon at Benjamin Mkapa National Stadium.
Karl Toko-Ekambi scored the decisive goal for the Indomitable Lions on the half-hour mark.
South Sudan 1-3 Mali
Ten-man Mali maintained their perfect winning record in Group G after thrashing South Sudan 3-1 on Thursday afternoon at St. Mary's Stadium in Kitende.
The Eagles went behind on the half-hour mark after an own goal by Boubakar Kouyate.
However, Mohamed Camara levelled matters for Mohamed Magassouba's charges just before the hour-mark.
The visitors were down to ten men in the last 12 minutes after Ibrahima Kone was red-carded for violent conduct but Sekou Koita and Aliou Dieng scored two quick goals in stoppages to rescue victory for Mali.
Guinea 1-0 Malawi
Guinea registered their first win and points in Group D after a last-gasp 1-0 win over Malawi on Thursday evening at Stade General Lansana Conte.
After a goalless first stanza, Liverpool midfielder broke the hearts of the Flames with the winner for the Syli National in stoppage time.
Guinea-Bissau 5-1 São Tomé e Principe
Guinea-Bissau had a flying start in Group A after drubbing Sao Tome and Principe 5-1 on Thursday evening at Stade d'Agadir.
Edmilson Viegas broke the deadlock for Sao Tome and Principe midway through the first stanza but Alfa Semedo equalised for the Djurtus towards the end of the first stanza.
Zinho Gano gave the home side the lead early in the second stanza, made it 3-1 and got his brace just before the hour-mark.
Baciro Conde's charges ran riot in the closing stages as Zidane Banjaqui and Jorginho added two further goals.
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